ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Ig heavy chain V region 1B43

Intramolecular
Cysteine 40 and cysteine 114
A redox-regulated disulphide may form within Ig heavy chain V region 1B43 between cysteines 40 and 114 (22 and 96 respectively in this structure).

Details

Redox score ?
80
PDB code
1kcv
Structure name
crystal structure of antibody pc282
Structure deposition date
2001-11-11
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
P18532
Residue number A
40
Residue number B
114
Peptide name
Ig heavy chain V region 1B43

Ligandability

Cysteine 40 of Ig heavy chain V region 1B43

Cysteine 114 of Ig heavy chain V region 1B43

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